Alpha-halocarboxylic acids and derivatives
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Filtered Search Results
Chemscene ChemScene | Methyl 6-bromohexanoate | 100G | CS-W015176 | 0.98 | 14273-90-6| MFCD00187528 | 209.08
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ChemScene | Methyl 6-bromohexanoate | 100G | CS-W015176 | 0.98 | 14273-90-6| MFCD00187528 | 209.08
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AdipoGen GE23077 A1 B1
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Chemical. CAS 752989-46-1, 752989-45-0752989-44-9. Formula C31H51N9O16, C31H49N9O16. MW 805.8803.8. Isolated from Actinomadura sp. Cyclic heptapeptide antibiotic. Potent and selective inhibitor of bacterial RNA polymerase RNAP. Inhibits Gram-positive Bacillus subtilis and Gram-negative Escherichia coli RNAPs with IC50 ~20nM, whereas it is not active on E. coli DNA polymerase or on eukaryotic wheat germ RNAP II IC50 values >100µM. Even though of its potent activity in vitro on purified bacterial RNAPs, it shows a narrow spectrum of antimicrobial activity in vivo on Gram-positive and Gram-negative bacteria, due to lack of memmbrane permeability. Acts at the level of transcription initiation. Binds directly to the bacterial RNA polymerase RNAP active-center i and i1 nucleotide binding sites, preventing the binding of initiating nucleotides and thereby preventing transcription initiation.
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Cayman Chemical Dynorphin A trifluoroacetate
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A heptadecapeptide that acts as an endogenous opioid receptor agonist (Kis = 0.5-1 nM for κ, µ, and δ); has been implicated in antinociceptive functions
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eMolecules 1878-67-7 | 2-(3-Bromophenyl)acetic acid | Synthonix - Stock | MFCD00004330 | 215.046 | C8H7BrO2 | 95.000 | OC(=O)Cc1cccc(Br)c1 | 100g | 495874663
2-(3-Bromophenyl)acetic acid | Synthonix - Stock | 1878-67-7 | MFCD00004330 | 215.046 | C8H7BrO2 | 95.000 | OC(=O)Cc1cccc(Br)c1 | 100g | 495874663
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Cayman Chemical trifluoroacetate salt 25mg
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A derivative of GLP-1
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eMolecules 5437-45-6 | Benzyl 2-bromoacetate | Ambeed | MFCD00000190 | 229.073 | C9H9BrO2 | 98.000 | BrCC(=O)OCc1ccccc1 | 25g | 525116708
Benzyl 2-bromoacetate | Ambeed | 5437-45-6 | MFCD00000190 | 229.073 | C9H9BrO2 | 98.000 | BrCC(=O)OCc1ccccc1 | 25g | 525116708
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![eMolecules 2923-18-4 | Sodium Trifluoroacetate | Accela ChemBio (ASD) | MFCD00013217 | 136.005 | C2F3NaO2 | 98.000 | [Na+].[O-]C(=O)C(F)(F)F | 10g | 588340268](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000158671.jpg-250.jpg)
eMolecules 2923-18-4 | Sodium Trifluoroacetate | Accela ChemBio (ASD) | MFCD00013217 | 136.005 | C2F3NaO2 | 98.000 | [Na+].[O-]C(=O)C(F)(F)F | 10g | 588340268
Sodium Trifluoroacetate | Accela ChemBio (ASD) | 2923-18-4 | MFCD00013217 | 136.005 | C2F3NaO2 | 98.000 | [Na+].[O-]C(=O)C(F)(F)F | 10g | 588340268
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Cayman Chemical MSG606 trifluoroacetate salt
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A peptide MC1R antagonist (IC50 = 17 nM); selectively binds to MC1R over MC3R and MC5R (IC50s = 3,900 and 1,000 nM, respectively), as well as MC4R at 10 µM; increases the latency to tail withdrawal in the tail-flick test in female, but not male, mice in a model of opioid-induced hyperalgesia at 7.5 UG/animal, i.c.v.; reduces protein levels of merlin in the cortex, reduces the number of surviving neurons in the cortex and hippocampal CA2 region, and increases the number of apoptotic cells in the cortex in rats 24 hours after injury in a model of controlled cortical impact-induced TBI at 1 nmol/animal, i.c.v.
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Sigma Aldrich Fine Chemicals Biosciences Ethyl bromoacetate-1-13C 99 atom % 13C | 61203-71-2 | MFCD00000194 | 1G
Ethyl bromoacetate-1-13C 99 atom % 13C | Purity: 99% (CP) | Mol Wt: 167.99 | 61203-71-2 | MFCD00000194 | 1G
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Medchemexpress LLC ODN 2216 sodium | DNA, d(G-sp-G-sp-G-G-G-A-C-G-A-T-C-G-T-C-G-sp-G-sp-G-sp-G-sp-G-sp-G), sodium salt | 5 MG
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ODN 2216 sodium acts as a type A CpG oligodeoxynucleotide vaccine adjuvant and a TLR9 agonist. It interacts with TLR9 in CD4+ T cells, activating pathways to induce type I interferons, IL-6, and TGF-β, and increasing intracellular ATP. It promotes anti-inflammatory T cell differentiation, inhibits proliferation, and enhances CD8+ T cell-mediated cytotoxicity against Mammaglobin-A in breast cancer. Used in breast cancer and systemic lupus erythematosus research.
- Type A CpG oligodeoxynucleotide vaccine adjuvant
- TLR9 agonist
- Modulates immune response via TLR9
- Induces type I interferons, IL-6, and TGF-β
- Increases intracellular ATP levels
- Promotes anti-inflammatory T cell differentiation
- Enhances CD8+ T cell cytotoxicity in breast cancer
- Relevant for breast cancer and lupus erythematosus studies
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Cayman Chemical Urumin trifluoroacetate salt
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An H1-selective influenza antiviral; inhibits H1 hemagglutinin-containing human influenza A viruses by 60 to >90%; intranasal administration of urumin (20 UG) prior to a lethal dose of PR8 influenza increases survival in mice
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Cayman Chemical trifluoroacetate salt 1mg
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An exendin-4 (3-39) amide derivative
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![eMolecules 19199-82-7 | 4-Nitrophenyl bromoacetate | Apollo Scientific | MFCD00051840 | 260.043 | C8H6BrNO4 | 0.000 | [O-][N+](=O)c1ccc(OC(=O)CBr)cc1 | 1g | 562440600](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502160436.JPG-250.jpg)
eMolecules 19199-82-7 | 4-Nitrophenyl bromoacetate | Apollo Scientific | MFCD00051840 | 260.043 | C8H6BrNO4 | 0.000 | [O-][N+](=O)c1ccc(OC(=O)CBr)cc1 | 1g | 562440600
4-Nitrophenyl bromoacetate | Apollo Scientific | 19199-82-7 | MFCD00051840 | 260.043 | C8H6BrNO4 | 0.000 | [O-][N+](=O)c1ccc(OC(=O)CBr)cc1 | 1g | 562440600
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eMolecules 535-83-1 | Medchem Express | Trigonelline | 10mg | 536984347 | HY-N0414 | MFCD00054262 | 137.138 | C7H7NO2
Medchem Express | Trigonelline | 10mg | 536984347 | HY-N0414 | 535-83-1 | MFCD00054262 | 137.138 | C7H7NO2
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Cayman Chemical trifluoroacetate salt 10mg
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An exendin-4 (3-39) amide derivative
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